Senior Bioinformatics Analyst

first_imgBaylor College of Medicine is an Equal Opportunity/AffirmativeAction/Equal Access Employer.6524CA; CH SummaryThe HGSC provides a unique opportunity to gain high-throughput dataproduction experience in an academic research environment, withopportunities for publication, conference travel and internationalscientific collaboration. As a member of the NGSI ClinicalInformatics team, you will directly contribute to the HGSC’spioneering work in Mendelian genomics and multiple NIH PrecisionMedicine initiatives.The next-generation sequencing informatics (NGSI) team oversees theday-to-day logistics of all NGS pipelines through the process ofmapping, alignment, variant calling and quality control. Withinthat larger group, the HGSC-CL informatics team focuses on thecenter’s growing list of clinical projects and partnerships. Themany well-defined and funded HGSC projects offer our talented staffthe freedom to innovate and the satisfaction of deliveringactionable results.This position will involve collaborating with teammates to developsoftware and pipelines to expand the types of variants detectablewith our clinical sequencing pipelines as well as tools fortertiary analysis of variants, including clinical classification.This position requires a high-performing bioinformatics programmerwith demonstrated exceptional communication, organization, andtime-management skills to assist in building and operating thesepipelines.Position is located at our main Baylor Campus in the Texas MedicalCenter.Job DutiesClinical Production Informatics At least 1 year of at-scale NGS experience.Experience working on large software engineering, projects,strong understanding of change management processes.AWS / Cloud services including cloudformation, batch, lambda,SNS, ECR, DynamoDBCAP/CLIA DocumentationHigh Performance Compute Environment (e.g., moab, PBS)Software testingNGS sequence analysis tools (e.g. BWA, Samtools, bedtools,Dragen) Preferred QualificationsMaster’s degree in a related field may be considered in lieu oftwo years of required experience.Experience in the following:Unix command line interfaceProgramming Language (python preferred; ruby, java, perl,C++)Familiarity with databases and sql.Gitcenter_img Benchmark new bioinformatics tools for inclusion in productionpipelines.Implement pipeline steps in AWS batch and lambda or local HPCsystem.Develop and deploy docker containers for pipelinecomponents.Support and troubleshooting pipelines.Interact with Project Managers, Clinical Geneticists, LIMS, andIT.Provide feedback to NGSI Production R&D.Build and maintain monitoring tools.Maintain documentation of software to CAP/CLIA standards.Perform other job-related duties as assigned, includingassisting the larger NGSI team as necessary. Minimum QualificationsBachelor’s degree in Genetics, Biology, Bioinformatics,Biostatistics, Computational Biology, Computer Science, or arelated field.Four years of relevant experience.last_img read more