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Higher blood pressure may be linked to brain disease and Alzheimer’s

first_imgShare LinkedIn Share on Twitter For the study, 1,288 older people were followed until they died, which was an average of eight years later. The average age at death was 89 years. Blood pressure was documented yearly for each participant and autopsies were conducted on their brains after death. The average systolic blood pressure for those enrolled in the study was 134 mmHg and the average diastolic blood pressure was 71 mmHg. Two-thirds of the participants had a history of high blood pressure, and 87 percent were taking high blood pressure medication. A total of 48 percent of the participants had one or more brain infarct lesions.Researchers found that the risk of brain lesions was higher in people with higher average systolic blood pressure across the years. For a person with one standard deviation above the average systolic blood pressure, for example 147 mmHg versus 134 mmHg, there was a 46 percent increased risk of having one or more brain lesions, specifically infarcts. For comparison, the effect of an increase by one standard deviation on the risk of having one or more brain infarcts was the equivalent of nine years of brain aging.Those with one standard deviation above the average systolic blood pressure also had a 46 percent greater chance of having large lesions and a 36 percent greater risk of very small lesions. Arvanitakis noted that an important additional result of the study was that people with a declining systolic blood pressure also had an increased risk of one or more brain lesions, so it was not just the level but also the declining blood pressure that was associated with brain lesions.Separately, higher average diastolic blood pressure was also related to brain infarct lesions. People who had an increase of one standard deviation from an average diastolic blood pressure, for example from 71 mmHg to 79 mmHg, had a 28 percent greater risk of one or more brain lesions.The results did not change when researchers controlled for other factors that could affect the risk of brain lesions, such as whether they used high blood pressure drugs.When looking for signs of Alzheimer’s disease in the brain at autopsy, researchers found a link between higher average late-life systolic blood pressure across the years before death and a higher number of tangles, but not plaques. Arvanitakis said this link is difficult to interpret and will need more research.“While our findings may eventually have important public health implications for blood pressure recommendations for older people, further studies will be needed to confirm and expand on our findings before any such recommendations can be made,” said Arvanitakis.Limitations of the study include that researchers did not have access to blood pressure of participants in middle age, only in later life, and that blood pressure information was recorded only once a year and not more frequently. Emailcenter_img Share on Facebook Pinterest Older people who have higher blood pressure may have more signs of brain disease, specifically brain lesions, according to a study published in the July 11, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers also found a link between higher blood pressure and more markers of Alzheimer’s disease, tangles in the brain.“Blood pressure changes with aging and disease, so we wanted to see what kind of impact it may have on the brain,” said study author Zoe Arvanitakis, MD, MS, of the Rush Alzheimer’s Disease Center at Rush University Medical Center in Chicago, and a Fellow of the American Academy of Neurology. “We researched whether blood pressure in later life was associated with signs of brain aging that include plaques and tangles linked to Alzheimer’s disease, and brain lesions called infarcts, areas of dead tissue caused by a blockage of the blood supply, which can increase with age, often go undetected and can lead to stroke.”Healthy blood pressure is less than 120/80 millimeters of mercury (mmHg). High blood pressure is above 140/90 mmHg. The higher number is called systolic blood pressure, the pressure in the blood vessels when the heart beats. The lower number is called diastolic blood pressure, the pressure when the heart is at rest.last_img read more

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Civmec awarded Gorgon, Persephone jobs

first_imgCivmec, the service provider for the oil industry said that it has been awarded $64 million of new projects while expanding some of the existing contracts.Besides work for Rio Tinto on the company’s mines in the Pilbara region, Civmec will be fabricating and testing Gorgon’s new 34 inch Subsea Pig Launcher/Receiver (SSPLR) in two stages, on behalf of GE Oil & Gas, the company said in a statement.Stage 1 works will commence immediately and involve the fabrication of a 34-inch barrel for a subsea pig receiver from supplied materials, with the complete structure weighing 104 tonnes. Completion of Stage 1 is scheduled for November 2015. Fabrication of a 6-inch kicker header, testing of the SSPLR and retrofitting will be carried out at a later date as part of Stage 2 works.Civmec also informed it will begin work on behalf of FMC Technologies for the fabrication, surface treatment and testing of a production manifold. The manifold is designed for installation at the Persephone project, located on Australia’s North West Shelf and is scheduled for completion by March 2016.[mappress mapid=”17381″]LNG World News Staff; Image: Civmeclast_img read more

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High School Baseball: Benton’s Horton co-MVP in District 1-4A

first_imgBenton’s Horton co-MVP in District 1-4ABenton sophomore Cole Horton has been named the co-Most Valuable Player on the All-District 1-4A baseball team selected by the district’s coaches.Horton, a catcher, helped the Tigers win their fifth straight district championship. Benton finished 32-9 after losing to Neville two games to one in the quarterfinals of the playoffs.Horton shares MVP honors with senior center fielder Drake Foster of runner-up North DeSoto.Benton placed 10 other players on the first team, including three pitchers — senior Will Hine, freshman Cameron Ross and junior Colby Sharp.Hine, the ace of the staff, went 10-1, including 3-0 in the playoffs.Other first-team selections were junior infielder Garrett Hable, senior infielder Connor Jack Smith, junior shortstop Cody Norris, sophomore outfielder Sam Simmons, senior outfielder Coleman Nerren, senior outfielder Hal Gatti and freshman designated hitter Cade Scott.Bossier junior infielder Kaleb Harlow made the first team as a utility player.Benton junior infielder Peyton Long made the second team.Bossier’s second-team selections were sophomore outfielder Xavier Murphy, junior pitcher Rangel Miller and junior outfielder Kevin McCuthen.Benton juniors Andrew McPherson and Kade Bailey and Bossier sophomore Chase Bounds were honorable mention selections.For a complete list of the All-District 1-4A team, go to bossierpress.comRussell [email protected] Expat InsuranceExpat Living in Hong Kong without Health Insurance?Top Expat Insurance|SponsoredSponsoredUndoNews gadgetThis watch takes the whole country by storm! it’s price? Ridiculous!News gadget|SponsoredSponsoredUndoTheTopFiveVPNThe Secret Netflix Doesn’t Want You To Know To Unblock RestrictionsTheTopFiveVPN|SponsoredSponsoredUndoPerfect-Dating.comAre You Ready to Meet Cool Guys in Tung Chung?Perfect-Dating.com|SponsoredSponsoredUndoTheTopFiveVPNThe Trick Netflix Doesn’t Want You To Know To Unlock RestrictionsTheTopFiveVPN|SponsoredSponsoredUndoCelebsland.com9 Celebrity Before-And-After Plastic Surgery DisastersCelebsland.com|SponsoredSponsoredUndolast_img read more

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The Russo Bros. aren’t too happy about Chris Pratt’s sneaky ‘Endgame’ Instagram spoiler

first_imgL-R Josh Brolin, Joe, Anthony Russo — Charley Gallay/Getty Images for Disney(LOS ANGELES) — It appears Star-Lord is every bit the outlaw he claims to be, according to Avengers: Endgame directors Joe and Anthony Russo.Millions have respectfully followed the Russos’ hashtag warnings to not spoil the Marvel blockbuster, but ever the renegade, Guardians of the Galaxy star Chris Pratt defied the brothers. This week, he dropped a sneakily-shot video from the Endgame set that showed virtually every star rehearsing a critical final battle. Pratt’s Instagram post alone attracted 20 million views and counting.The Russos say on May 6, their spoiler ban is over, which is why an exasperated Joe Russo laughed to ABC Radio,  “If we had our druthers, Pratt would’ve held onto that video until this Monday.”The lifting of the ban comes as a relief to the pair, though.“It literally is like working for the CIA for a year,” Joe says. “You really have to train your mind not to give anything away in casual conversation with people.”Anthony chimed in, “We’re the type of people that enjoy the dialogue about movies almost as much as we enjoy movies,  so…yeah, to be able to finally get to…where we can all freely discuss it is exciting for us!”While moviegoers haven’t actually filmed the movie, they’ve been recording and posting their audible reactions to the film — and The Russos have been watching.“That was something we really discovered on Infinity War,” Anthony says of Endgame‘s predecessor. “[J]ust to see the audience reaction…just to watch people explode! It’s thrilling…! You don’t see that in a movie theater very often.”Twitter just announced that a record 50 million Endgame-related tweets have been sent. Marvel Studios is owned by Disney, the parent company of ABC News.last_img read more

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